animal experimentation

Animal Experimentation Services for preclinical validation and biomedical research

At Duponte we offer a complete and ethical service for studies that require animal models in biomedical research, compound validation or functional analysis.

We work with murine models in authorized and controlled conditions, and we accompany each project from the experimental design to the interpretation of results. All this with the support of certified facilities and expert personnel in animal welfare and regulations.

animal experimentation

Customized projects with a scientific, ethical and technical approach

Our solutions are adapted to each particular case, to cover with guarantees all the phases of a study with experimental animals.

Asesoramiento

Ethical and legal advice

  • Complete management of documentation for project authorization
  • Coordination with the Animal Experimentation Ethics Committee (CEEA)
  • Support in experimental design and scientific justification

Experimentation with murine models

We work with strains such as C57BL/6J, C57BL/6N, Balb/c and CD-1, adapting to the objectives of each study.

Types of studies available:

  • Preclinical evaluation of drugs or compounds
  • In vivo validation of biomarkers
  • Murine models for neurodegenerative, inflammatory or metabolic diseases
  • Studies on oxidative stress and systemic inflammation
  • Microbiota-diet interaction and gut health
  • Toxicity and safety assays
  • Tissue regeneration and cell differentiation
  • Reproductive biology and regenerative medicine.
Rata
Duponte
Duponte movimiento
animal experimentation

Technical capabilities and associated tests

We have technical capabilities for functional, hitological and molecular analysis of biological samples from in vivo studies. These services can be integrated into complete projects or contracted separately.

Técnicas in vivo

In vivo techniques

  • Oral, intraperitoneal (IP), subcutaneous (SC) and intravenous (IV) administration of compounds
  • Dose escalation and clinical follow-up
  • Recording of variables such as weight, behavior, clinical signs and survival

Functional and behavioral assessment

  • Motor, cognitive and sensory testing
  • Behavioral analysis
Evaluación funcional
Procesamiento histológico

Histological processing and tissue analysis

  • Standardized necropsies and organ harvesting
  • Fixation, kerosene embedding or cryopreservation
  • Histological sections with microtome or cryostat
  • Basic stains
  • Immunohistochemistry (IHQ) and immunofluorescence (IF)

Genomic molecular assays

  • DNA and RNA extraction
  • PCR, qPCR and RT-qPCR
  • ELISA and Western Blot
  • Genomics (DNA-seq)
  • Transcriptomics (RNA-sep, scRNA-seq)
ensayos
Ensayos inmunológicos

Immunological assays

  • Hormone, protein and key gene analysis
  • Immune expression profiling
  • Cytometry
animal experimentation

Analysis and interpretation of results

We do not only execute the study: we can also contract the scientific analysis and interpretation so that each piece of data becomes applicable knowledge.

Carga tus datos genéticos

Data processing
and biological images

Carga tus datos genéticos

Statistical analysis
and graphical representation

Carga tus datos genéticos

Clinicopathologic correlation
with client data

Carga tus datos genéticos

Preparation of
complete final reports

animal experimentation

Why trust Duponte for your in vivo validation?

  • Certified and controlled facilities (CITIUS, University of Seville)
  • Accredited personnel
  • Ideal for centers without their own animal facilities or that need to outsource this phase
  • Commitment to the 3Rs, scientific quality and bioethics
  • Collaborative network with other institutions
  • Personalized attention and continuous communication throughout the project
Duponte
Do you have a project that requires experimental validation or preclinical support?

We help you to design, execute and interpret it with scientific rigor
and ethical commitment.

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