Animal Experimentation Services for preclinical validation and biomedical research
At Duponte we offer a complete and ethical service for studies that require animal models in biomedical research, compound validation or functional analysis.
We work with murine models in authorized and controlled conditions, and we accompany each project from the experimental design to the interpretation of results. All this with the support of certified facilities and expert personnel in animal welfare and regulations.
animal experimentation
Customized projects
with a scientific, ethical
and technical approach
Our solutions are adapted to each particular case, to cover with guarantees all the phases of a study with experimental animals.
Ethical and legal advice
Complete management of documentation for project authorization
Coordination with the Animal Experimentation Ethics Committee (CEEA)
Support in experimental design and scientific justification
Experimentation with murine models
We work with strains such as C57BL/6J, C57BL/6N, Balb/c and CD-1, adapting to the objectives of each study.
Types of studies available:
Preclinical evaluation of drugs or compounds
In vivo validation of biomarkers
Murine models for neurodegenerative, inflammatory or metabolic diseases
Studies on oxidative stress and systemic inflammation
We have technical capabilities for functional, hitological and molecular analysis of biological samples from in vivo studies. These services can be integrated into complete projects or contracted separately.
In vivo techniques
Oral, intraperitoneal (IP), subcutaneous (SC) and intravenous (IV) administration of compounds
Dose escalation and clinical follow-up
Recording of variables such as weight, behavior, clinical signs and survival
Functional and behavioral assessment
Motor, cognitive and sensory testing
Behavioral analysis
Histological processing
and tissue analysis
Standardized necropsies and organ harvesting
Fixation, kerosene embedding or cryopreservation
Histological sections with microtome or cryostat
Basic stains
Immunohistochemistry (IHQ) and immunofluorescence (IF)
Genomic molecular assays
DNA and RNA extraction
PCR, qPCR and RT-qPCR
ELISA and Western Blot
Genomics (DNA-seq)
Transcriptomics (RNA-sep, scRNA-seq)
Immunological assays
Hormone, protein and key gene analysis
Immune expression profiling
Cytometry
animal experimentation
Analysis and interpretation
of results
We do not only execute the study: we can also contract the scientific analysis and interpretation so that each piece of data becomes applicable knowledge.
Data processing and biological images
Statistical analysis and graphical representation
Clinicopathologic correlation with client data
Preparation of complete final reports
animal experimentation
Why trust Duponte for your in vivo validation?
Certified and controlled facilities (CITIUS, University of Seville)
Accredited personnel
Ideal for centers without their own animal facilities or that need to outsource this phase
Commitment to the 3Rs, scientific quality and bioethics
Collaborative network with other institutions
Personalized attention and continuous communication throughout the project
Do you have a project
that requires experimental validation or preclinical support?
We help you to design, execute and interpret it with scientific rigor and ethical commitment.